Förlagets beskrivning
Building upon the foundation set in the first edition, Statins: The HMG-CoA
Reductase Inhibitors in Perspective examines existing and emerging statins and
their beneficial effectiveness in reducing serum cholesterol. The breadth of
coverage and depth of information in this book provide an authoritative guide
to statins from their discovery through the major clinical trials to the
present and explores the future of statin trials and lipid-lowering therapy
beyond statins.The book tells the story of statins, for the most part in the
words of those who lived it. The major clinical trials from Scandinavia, North
America, Australia, New Zealand, and Scotland are detailed by those who
conducted them. The book includes information on the pharmacology and
mechanisms of action, the statin angiographic trials, the use of statins after
vascular surgery, guidelines for the use of the statins in clinical practice,
and the cost-effectiveness of statin therapy. New chapters cover combination
therapy in lipid-lowering, new 'Megatrials' (HPS and PPP), and the PROSPER
study. What is a statin? A powerful lipid-lowering agent. Its main action is to
lower the low-density lipoprotein cholesterol level, thereby reducing the
overall cholesterol level in the blood. In this new edition of this text, the
authors examine the existing and emerging statins and their beneficial
effectiveness in reducing serum cholesterol.
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Statins
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